When David Hodges goes missing, the CSI team searches for any piece of evidence that can help locate him, clear his name, and save the reputation of the lab.

The CSIs investigate the murder of a dominatrix found near her secret sex dungeon.

As Halloween descends on Sin City, the CSIs investigate when a creepy mannequin prop inside a popular haunted house turns out to be a real dead body. Also, Catherine enlists the help of Folsom to search for her friend who disappeared.

The CSI team investigates after a group of teens discover a dead woman behind the wheel of an abandoned car in a Nevada ghost town.

The CSI team investigates the eccentric world of sideshows when a couple of performers are discovered burnt in a pit. Hodges mulls a plea deal as as his criminal trial kicks off.

When three masked assailants invade a home and murder an entire family, including a pregnant woman, the CSIs are called to the scene to investigate. Catherine leads the team through the emotional case, which intensifies her own longing to reconnect with her estranged daughter, Lindsey.

After all the guests attending an upscale fund raising soiree for the science department at a local university fall ill, the CSI team gears up to investigate. Also, Catherine enlists Grace's roommate to help her find clues after Grace disappears.

Max leads her team to investigate the death of a prestigious Michelin-starred chef found hanging in his restaurant's walk-in freezer.

A mysterious big foot-like footprint found near a crime scene puzzles the CSI team as they work to uncover who or what killed a father and son

Catherine's frustration intensifies when a lead suspect in Grace's disappearance is found murdered. The team exhausts all their skills to figure out who killed the suspect, and if his death will lead them to Grace.

When the bodies of two Regency Romantic Festival attendees are discovered, the CSI team uncovers a shocking link between their murders and previous cases.

A social media influencer party ends with the brutal murder of a popular guest. Chris Park's side hustle makes him uniquely qualified to lead the CSI team in their investigation.

When a young, non-verbal boy is found hiding in a stranger's garage, the CSI team searches for his missing mother. Also, Max receives a strange letter with symbols in silver ink that Folsom and Allie recognize from prior crime scenes.

Catherine's day off with her granddaughter gets interrupted when a woman wakes up from a four-year coma and remembers details from the night her sister died.

The CSI team investigates the death of an archaeologist found near the breakthrough discovery of an ancient civilization. Also, Max locates another cryptic note written in familiar silver ink after a woman kills her attacker.